Melamine foam is used as insulation, soundproofing material and in polymeric cleaning products, such as Magic Eraser.

Melamine is one of the major components in, a colorant in inks and plastics.

Melamine also enters the fabrication of melamine poly-sulfonate used as superplasticizer for making high-resistance concrete. Sulfonated melamine formaldehyde (SMF) is a polymer used as cement admixture to reduce the water content in concrete while increasing the fluidity and the workability of the mix during its handling and pouring. It results in concrete with a lower porosity and a higher mechanical strength, exhibiting an improved resistance to aggressive environments and a longer lifetime.

The use of melamine as fertilizer for crops had been envisaged during the 1950s and 1960s because of its high nitrogen content (2/3).[8] However, melamine is much more expensive to produce than are other common nitrogen fertilizers, such as urea. The mineralization (degradation to ammonia) for melamine is slow, making this product both economically and scientifically impractical for use as a fertilizer.